000 04562nam a2200349 a 4500
003 MX-TeUDD
005 20231106190708.0
008 050623s2004 ne gr 001 0 eng c
020 _a1586034944
020 _a9781586034948
022 _a0888-6008
040 _aMX-TeUDD
_bspa
_cMX-TeUDD
050 0 4 _aQR181
_b.I4 2004
245 0 0 _aImmunology of breast cancer /
_cedited by Wei-Zen Wei and Diana M. Lopez.
260 _aHolanda :
_bIOS Press,
_c2004
300 _a153 p. ;
_b26 cm.
505 8 _aIntroduction / Wei-Zen Wei.-- 1. Peptide-based vaccines in breast Cancer / M.L. Disis, L.G. Salazar and K.L. Knutson.-- 2. Augmenting the potency of breast cancer vaccines: combined modality immunotherapy / L.A. Emens, R.T. Reilly and E.M. Jaffee.-- 3. Her2/neu as a paradigm of a tumor-specific target for therapy / A. Choudhury and R. Kiessling.-- 4. Immunobiology of her-2/neu transgenic. mice / T. Pannellini, G. Forni and P. Musiani.-- 5. From breast cancer immunobiology to her-2 DNA vaccine and autoimmune sequelae / F. Miller, R.F. Jones, J. Jacob, Y.M. Kong and W.-Z. Wei.-- 6. Therapeutic efficacy of muc1-specific cytotoxic t. lymphocytes and CD 137 CO-stimulation / in a Spontaneous Breast Cancer Model P. Mukherjee, T.L. Tinder, G.D. Basu, L.B. Pathangey L. Chen and S.J. Gendler.-- 7. Dendritic cell- based therapeutics for breast cancer / S.A. Pilon-Thomas, M.E. Verhaegen and J.J. Mulé.-- 8. Glycoprotein Tumor Antigens for Immunotherapy of Breast Cancer / A.M. Vlad and O.J. Finn.-- 9. DNA Vaccines Suppress Angiogenesis and Protect Against Growth of Breast Cancer Metastases / N. Mizutani, Y. Luo, M. Mizutani, R.A. Reisfeld and R. Xiang.-- 10. Immune Tolerance in Breast Cancer / F. Cheng, D. Gabrilovich and E. M. Sotomayor.-- 11. HLA Antigen Changes in Malignant Tumors of Mammary Epithelial Origin: Molecular Mechanisms and Clinical Implications / M. Campoli, C.-C. Chang, S.A. Oldford, A.D. Edgecombe, S. Drover and S. Ferrone.-- 12. Antagonists of Tumor-Specific Immunity: Tumor-Induced Immune Suppression and Host Genes that Co-opt the Anti-Tumor Immune Response / S. Ostrand-Rosenberg, P. Sinha, E.A. Danna, S. Miller, C. Davis and S.K. Dissanayake.-- 13.The Role of Chemokines in the Biology and Therapy of Breast Cancer / T.C. Walser and A.M. Fulton.-- 14. T Cell-Derived Matrix Metalloproteinase-9 in Breast Cancer: Friend or Foe? / J.L. Owen, V. Iragavarapu-Charyulu and D.M. Lopez.
520 2 _aIn this issue, exciting new directions are outlined by fourteen groups of investigators working on critical areas in 'Breast Cancer Immunology'. In the clinic, patients are responding to Her-2 peptides or GM-CSF transfected tumor cell vaccines. Futhermore, tumors under vaccine induced immune attack can prime the host to additional antigens. Selected chemotherapeutic agents are used to further vaccine efficacy. These promising results highlight the value of breast cancer immunotherapy. Although the clinical progress is exciting, significant challenges remain. Many tumor-associated antigens are self-antigens and vigorous measures will be required to induce consistent and sustained anti-tumor immunity. There is a pressing need for new immunotherapy targets. In this issue, the better-characterized glycoprotein antigens and novel molecules in angiogenesis are examined as new targets of breast cancer vaccines or immunotherapy. Continued effort in new antigen identification will be critical to cancer control. Finally, a reality check is warranted. Most breast cancer cells are still elusive to immune intervention. The mechanisms of such evasion are under intense investigation and much progress has been made. Alteration in antigen processing machinery is a major route of tumor evasion.
526 8 _aSalud
650 0 _aBreast neoplasms
_xDrug therapy.
_979295
650 0 _aMamas
_xTumores
_xTratamiento.
_979296
650 0 _aQuimioterapia.
_99029
650 0 _aCáncer
_xInvestigaciones.
_979297
650 0 _aMamas
_xCáncer
_xInvestigaciones.
_979298
700 1 _aLopez, Diana M.,
_eed.
_979299
700 1 _aWei, Wei-Zen,
_eed.
_979300
856 _uhttps://books.google.com.mx/books?id=fSbe2g9T3loC&printsec=frontcover
_zVista previa (Google Books).
856 _uhttps://web.archive.org/web/20231107015919/https://books.google.com.mx/books/content?id=fSbe2g9T3loC&pg=PP1&img=1&zoom=3&hl=en&sig=ACfU3U3IJLNYbcW2UrG8XJA6WWMSfjj_gQ&w=1280
_zPortada (Wayback Machine, Internet archive. 6-nov-2023).
905 _aAcervo
906 _aPaty
_b20050623
942 _cBK01
_2lcc
999 _c268744
_d268744
907 _c1
_dAlejandro Alberto Castrejón Murillo