TY - BOOK AU - Micozzi,Marc S. AU - Moon,Thomas E. TI - Nutrition and cancer prevention: investigating the role of micronutrients SN - 0824779932 AV - RC268 .N8 1989 PY - 1989/// CY - New York PB - Marcel Dekker KW - Pruebas clínicas KW - Cáncer KW - Aspectos nutricionales KW - Prevención KW - Oligoelementos en la nutrición N1 - Incluye referencias bibliográficas; Part 1. Rationale for nutritional prevention of cancer.-- 1. General Introduction: Rationale for the Nutritional Prevention of Cancer / Marc S. Micozzi and Joseph A. Tangrea.-- 2. Mechanisms for Nutritional Inhibition of Carcinogenesis / John A. Milner.-- 3. Experimental Evidence on the Nutritional Prevention of Cancer / Paul M. Newberne, Thomas F. Schrager, and Michael W. Conner.-- 4. Human Epidemiological Evidence on the Nutritional Prevention of Cancer / David J. Hunter and Walter C. Willett.-- Part 2. Methodologic issues for nutritional assessment.-- 5. Analysis of Micronutrients in Foods / Gary R. Beecher and Frederick Khachik.-- 6. Dietary Assessment Methods / Gladys Block and Anne M. Hartman.-- 7. Methods for Determination of Retinoids, a-Tocopherols, and Carotenoids in Human Serum, Plasma and Other Tissues / David W. Nierenberg, Yei-Mei Peng, and David S. Alberts.-- Part 3. Evidence on micronutrients and cancer prevention.-- 8. Foods, Micronutrients, and Reduction of Human Cancer / Marc S. Micozzi.-- 9. Retinoids for the Prevention of Cancer / Scott M. Lippman and Frank L. Meyskens, Jr.-- 10. B-Carotene, Canthaxanthin, and Phytoene / Micheline M. Mathews-Roth.-- 11. Calcium, Vitamin D, and the Prevention of Gastrointestinal Cancer / Michael J. Wargovich.-- 12. a-Tocopherols (Vitamin E) / William J. Mergens and Hemmige N. Bhagavan.-- 13. Ascorbic Acid in Cancer Prevention / Gladys Block and Marilyn Menkes.-- 14. Selenium / Gerald F. Coombs, Jr.-- Part 4. Planning, conduct, and interpretation of cancer prevention trials.-- 15. Approach to Selection of Agents for Cancer Prevention Trials / Thomas E. Moon.-- 16. Design of Prevention Trials / Stephen Piantadosi and David P. Byar.-- 17. Choice of Populations for Cancer Prevention Trials / Meir J. Stampfer, Walter C. Willett, and Charles H. Hennekens.-- 18. The Effects of Subject Selection Factors in Cancer Prevention Trials / Curtis J. Mettlin.-- 19. Endpoint Identification: Selection and Ascertainment / Blossom H. Patterson and Stephen Piantadosi.-- 20. Practical Aspects of Cancer Prevention Trials / Marguerite Stevens, E. Robert Greenberg, and John A. Baron.-- 21. Data and Safety Monitoring / David L. DeMets.-- 22. Aspects of the Analysis and Reporting of Cancer Prevention Trials / Ross L. Prentice and Stephen G. Self.-- 23. Future Strategies for Cancer Prevention Trials / Frank L. Meyskens, Jr.-- ; Salud N2 - Scientific advances have led to the recognition that many chronic diseases such as cancer may be preventable. In this volume, 36 contributions test cancer prevention hypotheses, attempt to interpret their results, and provide a guide to the background, rationale, and selection of cancer prevention agents, as well as the design, implementation, and evaluation of cancer prevention studies. It will offer assistance to many in the conduct of investigations and will be of interest to all in the interpretation of research results in the scientific literature. ER -